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Description
Weight loss drugs such as Ozempic were in the headlines a lot in 2025 and patent protections for these drugs expire in some countries in 2026. In this edition of #PeriodicGraphics in @ LY3437943, a novel triple glucagon, GIP, and GLP 1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept: Cell Metabolism Effects of Glucagon like Peptide 1 Receptor Agonists on Skin Homeostasis and Skin Aging Processes Beyond GLP 1: The next wave of incretin based obesity treatments GIP GLP 1 dual agonists (e.g., #Tirzepatide) weight loss vs. GLP 1 alone Triple agonists (GIP GLP 1 Glucagon) aim for >25% weight loss
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Best in 7 days
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Best in 7 days
Best in 7 days
4.8 ★★★★★
Based on 1046 reviews
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Product Reviews
★★★★★ 4
Seems to have helped
Bought a used 2020 Jeep Sahara 2 liter turbo charged with 80k miles from a dealership. Dealership had just changed oil the day of purchase. Drove it home 30 miles down interstate and another 20 back roads, it ticked and tapped allot at idle and the dip stick was varnished.
I added the flush, let it idle for 10 minutes and drained it. The new oil from the dealership drained out jet black, no light could pass thru it.
I changed the oil with Walmart oil and a cheap oil filter and let it idle for 5 minutes to clean out all the engine flush, it drained out clean and clear.
I refilled it with Pennzoil Platinum High Mileage oil and a Fram Ultra Synthetic oil filter. It's been a week and the engine is noticeably quieter and smoother since using this product.
If nothing else it cleaned allot of carbon from inside of my engine.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 25, 2025
★★★★★ 5
HOLY CRAP!!!!
So my 2005 Durango has a 5.7 and I put on 253,000 miles on it before it blew a head gasket. Since it was summer, iI decided I'd tackle it myself. The upper end was so full of gunk, I can't believe I hadn't had serious issues. Anyway, I apparently dropped some pieces of crud down the oil channels, 'cuz after putting it all back together, I got alarms for low oil pressure. Figuring I'd try anything else before replacing the oil pump, i gave this stuff a try. WOW!!!! Not only did the oil pressure return, the engine runs SO much smoother! I had forgotten how smooth it ran when it was new. The caveat is that apparently the gunk was the only thing keeping some areas from leaking - as it lost oil at a startling rate. 1 bottle of the Liqui Oil Saver though, and within a week the oil leaks completely stopped.
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Reviewed in the United States on November 8, 2025
★★★★★ 5
Awesome!!
Had a check engine light come on for cam shaft position. Did some research online about the specific code and found that I could be due to sludge in the engine. Added this and ran for about 30 minutes and then had the oil changed.
The light never came back on and the engine is running smooth and quiet.
Will definitely use again.
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Reviewed in the United States on April 5, 2026
★★★★★ 5
Great product
This brand is great. The car is running great
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Reviewed in the United States on March 4, 2026
★★★★★ 5
Well worth the money.
I use nothing but Wix filters; they are the best
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Reviewed in the United States on April 22, 2026
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